1,615 research outputs found

    Historic Changes (1941–2008) In Side Channel And Backwater Habitats On An Unchannelized Reach Of The Missouri River

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    Flow regulation has had pervasive effects on aquatic ecosystems within the world’s large rivers. While channelization on the lower Missouri River has led to major changes in the river and its floodplain, including the loss of shallow water habitats, effects of upstream dams on unchannelized reaches on the Missouri have not been formally assessed. We quantified changes in the number and size of off-channel habitats, specifically backwaters and side channels, on the 95-km unchannelized reach of the Missouri below Gavins Point Dam (Yankton, South Dakota) using historical (1941, 1983–1985, 2008) aerial imagery. Total and mean areas of side channels declined by 77% and 37% and total and mean length decreased by 79% and 42% from 1941 to 2008. Total area of backwaters increased by 40% from 1941 to 2008, whereas mean area decreased by 36%. Our findings suggest that sharp declines in the area and length of side channels have occurred on this unchannelized remnant reach of the Missouri River, with likely significant impacts on aquatic ecosystem processes

    Peroxidase-dependent metabolism of benzene's phenolic metabolites and its potential role in benzene toxicity and carcinogenicity.

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    The metabolism of two of benzene's phenolic metabolites, phenol and hydroquinone, by peroxidase enzymes has been studied in detail. Studies employing horseradish peroxidase and human myeloperoxidase have shown that in the presence of hydrogen peroxide phenol is converted to 4,4'-diphenoquinone and other covalent binding metabolites, whereas hydroquinone is converted solely to 1,4-benzoquinone. Surprisingly, phenol stimulates the latter conversion rather than inhibiting it, an effect that may play a role in the in vivo myelotoxicity of benzene. Indeed, repeated coadministration of phenol and hydroquinone to B6C3F1 mice results in a dramatic and significant decrease in bone marrow cellularity similar to that observed following benzene exposure. A mechanism of benzene-induced myelotoxicity is therefore proposed in which the accumulation and interaction of phenol and hydroquinone in the bone marrow and the peroxidase-dependent formation of 1,4-benzoquinone are important components. This mechanism may also be responsible, at least in part, for benzene's genotoxic effects, as 1,4-benzoquinone has been shown to damage DNA and is shown here to induce multiple micronuclei in human lymphocytes. Secondary activation of benzene's phenol metabolites in the bone marrow may therefore play an important role in benzene's myelotoxic and carcinogenic effects

    Pressure Modulator Radiometer (PMR) tests

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    The pressure modulator technique was evaluated for monitoring pollutant gases in the Earth's atmosphere of altitude levels corresponding to the mid and lower troposphere. Using an experimental set up and a 110 cm sample cell, pressure modulator output signals resulting from a range of gas concentrations in the sample cell were examined. Then a 20 cm sample cell was modified so that trace gas properties in the atmosphere could be simulated in the laboratory. These gas properties were measured using an infrared sensor

    Solving multi-criteria decision problems under possibilistic uncertainty using optimistic and pessimistic utilities

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    International audienceThis paper proposes a qualitative approach to solve multi-criteria decision making problems under possibilistic uncertainty. De-pending on the decision maker attitude with respect to uncertainty (i.e. optimistic or pessimistic) and on her attitude with respect to criteria (i.e. conjunctive or disjunctive), four ex-ante and four ex-post decision rules are dened and investigated. In particular, their coherence w.r.t. the principle of monotonicity, that allows Dynamic Programming is studied

    Bacteriophage lambda N protein alone can induce transcription antitermination in vitro.

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    Second-Order Belief Hidden Markov Models

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    Hidden Markov Models (HMMs) are learning methods for pattern recognition. The probabilistic HMMs have been one of the most used techniques based on the Bayesian model. First-order probabilistic HMMs were adapted to the theory of belief functions such that Bayesian probabilities were replaced with mass functions. In this paper, we present a second-order Hidden Markov Model using belief functions. Previous works in belief HMMs have been focused on the first-order HMMs. We extend them to the second-order model

    Theory of Cylindrical Tubules and Helical Ribbons of Chiral Lipid Membranes

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    We present a general theory for the equilibrium structure of cylindrical tubules and helical ribbons of chiral lipid membranes. This theory is based on a continuum elastic free energy that permits variations in the direction of molecular tilt and in the curvature of the membrane. The theory shows that the formation of tubules and helical ribbons is driven by the chirality of the membrane. Tubules have a first-order transition from a uniform state to a helically modulated state, with periodic stripes in the tilt direction and ripples in the curvature. Helical ribbons can be stable structures, or they can be unstable intermediate states in the formation of tubules.Comment: 43 pages, including 12 postscript figures, uses REVTeX 3.0 and epsf.st

    Delusional beliefs and reason giving

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    Delusions are often regarded as irrational beliefs, but their irrationality is not sufficient to explain what is pathological about them. In this paper we ask whether deluded subjects have the capacity to support the content of their delusions with reasons, that is, whether they can author their delusional states. The hypothesis that delusions are characterised by a failure of authorship, which is a dimension of self knowledge, deserves to be empirically tested because (a) it has the potential to account for the distinction between endorsing a delusion and endorsing a framework belief; (b) it contributes to a philosophical analysis of the relationship between rationality and self knowledge; and (c) it informs diagnosis and therapy in clinical psychiatry. However, authorship cannot provide a demarcation criterion between delusions and other irrational belief states
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